N-(3,5-Dimethylphenyl)succinamic acid
نویسندگان
چکیده
In the title compound, C(12)H(15)NO(3), the N-H and C=O bonds are anti to each other. The C=O and O-H bonds of the acid group display an anti-periplanar orientation relative to each other. The crystal packing features a three-dimensional network of molecules held together by O-H⋯O and N-H⋯O hydrogen bonds.
منابع مشابه
N-(2,6-Dimethylphenyl)succinamic acid
In the amide segment of the title compound, C(12)H(15)NO(3) {systematic name: 3-[(2,6-dimethyl-phen-yl)amino-carbon-yl]propionic acid}, the N-H and C=O bonds are anti to each other. The mol-ecules are packed into a two-dimensional array via N-H⋯O and O-H⋯O hydrogen bonds.
متن کاملN-(3,4-Dimethylphenyl)succinamic acid
The asymmetric unit of the title compound, C(12)H(15)NO(3), contains two independent mol-ecules. In both mol-ecules, the conformations of the amide oxygen and the carbonyl O atom of the acid segment are anti to the adjacent CH(2) groups. In the crystal, both molecules form inversion dimers linked by pairs of O-H⋯O hydrogen bonds and N-H⋯O interactions link the dimers into [100] chains.
متن کاملN-(2,3-Dimethylphenyl)succinamic acid
In the title compound, C(12)H(15)NO(3), the conformations of N-H and C=O bonds in the amide segment are anti to each other and that of the amide H atom is syn to the ortho- and meta-methyl groups in the benzene ring. In the crystal, the mol-ecules are linked into infinite chains through inter-molecular O-H⋯O and N-H⋯O hydrogen bonds.
متن کامل2-(2,4-Dichlorophenyl)-3-[5-(3,5-dimethylphenyl)-1,3,4-thiadiazol-2-yl]thiazolidin-4-one
The title compound, C(19)H(15)Cl(2)N(3)OS(2), was synthesized by the reaction of N-(2,4-dichloro-phen-yl)-5-(3,5-dimethyl-phen-yl)-1,3,4-thia-diazol-2-amine and mercaptoacetic acid. The thia-zolidinone ring adopts a twist conformation. The 2,4-dichloro-phenyl ring is almost perpendicular to the thia-diazole ring, the dihedral angle being 82.8 (2)°. The 3,5-dimethyl-phenyl ring is nearly coplana...
متن کاملIn vivo metabolism and disposition of the nephrotoxicant N-(3, 5-dichlorophenyl)succinimide in Fischer 344 rats.
N-(3,5-Dichlorophenyl)succinimide (NDPS) was originally developed as an agricultural fungicide. Previous work indicated that NDPS-induced renal damage in rats is metabolism-dependent and that hydroxylated metabolites might be involved in the nephrotoxic response. In this study, the disposition and nephrotoxicity of [14C]NDPS at two time points (3 and 24 hr) and three doses (0.2, 0.4, and 0.6 mm...
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عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2010